Preheat your oven to 375°F (190°C). Lightly grease a baking dish to hold the crab mixture.
Gently fold the lump crab meat into a mixing bowl, taking care to keep it as whole as possible for texture.
In a separate bowl, melt the butter and sauté the minced garlic until fragrant and just starting to turn golden, about 30 seconds.
Pour the garlic butter mixture over the crab, then add Worcestershire sauce, mayonnaise, and lemon juice. Gently mix everything until evenly combined, avoiding breaking up the crab too much.
Season the mixture with Old Bay, salt, and pepper, then give it a final gentle fold to distribute the seasoning evenly.
Transfer the crab mixture into the prepared baking dish, spreading it into an even layer.
Sprinkle the panko breadcrumbs over the top of the crab mixture, creating a crumbly, golden layer that will crisp as it bakes.
Bake in the preheated oven until the top is golden brown and bubbling around the edges, about 20 minutes.
Remove from the oven and let it rest for a few minutes; the aroma of garlic, butter, and seasoned crab will fill the air.
Serve the Crab Imperial hot, with crusty bread or lemon wedges on the side for an extra burst of freshness.